Part I Test Plan

1. Topographical Anatomy (11%)

• Planes of the body and anatomical terminology
• Head and neck
• Back and thorax
• Abdomen, pelvis and perineum
• Upper and lower limbs
• Integument (including histology)

2. Osteology of the Appendicular Skeleton (13%)

• Upper limb and shoulder girdle
• Lower limb and pelvis
• Development
• Histology

3. Arthrology and Syndesmology of the Appendicular Skeleton (11%)

• Classification of joints
• Articulations of the appendicular skeleton
• Biomechanics

4. Myology of the Appendicular Skeleton (12%)

• Upper limb and shoulder (including innervation)
• Lower limb and pelvic girdle (including innervation)
• Development
• Structure and histology

5. Cardiovascular and Lymphatic Systems (11%)

• Heart
• Arteries
• Veins
• Lymphatic vessels and lymphoid tissue (including spleen and thymus)
• Development
• Histology

6. Digestive System (11%)

• Oral cavity and pharynx
• Digestive viscera
• Development
• Histology

7. Respiratory System (11%)

• Nose and sinuses
• Larynx, trachea and bronchi
• Lungs, pleura and mediastinum
• Development
• Histology

8. Urogenital System (10%)

• Urinary organs
• Male reproductive organs
• Female reproductive organs
• Development
• Histology

9. Endocrine System (10%)

• Endocrine glands and tissues
• Development
• Histology

1. Osteology of the Axial Skeleton (18%)

• Skull
• Vertebral column
• Ribs and sternum
• Development

2. Myology of the Axial Skeleton (17%)

• Face and head
• Back and neck
• Thorax and abdomen
• Pelvis and perineum
• Development

3. Arthrology and Syndesmology of the Axial Skeleton (14%)

• Classification of joints
• Articulations of the axial skeleton
• Biomechanics

4. Anatomy of the Central Nervous System and Related Structures (18%)

• Cerebrum
• Brainstem and cerebellum
• Spinal cord and meninges
• Vascular supply and relationships
• Ventricles and cerebrospinal fluid
• Development
• Histology

5. Anatomy of the Peripheral and Autonomic Nervous Systems (19%)

• Spinal nerves, plexuses, and branches
• Cranial nerves
• Visceral innervation
• Cutaneous innervation
• Development
• Histology

6. Organs of Special Senses (14%)

• Vision
• Audition and equilibrium
• Olfaction
• Gustation
• Development
• Histology

1. Neurophysiology (12%)

• Membrane potentials, action potentials, and synaptic transmission
• Motor function
• Sensory function
• Autonomic function
• Higher cortical function
• Special senses

2. Muscle Physiology (12%)

• Cardiac muscle
• Skeletal muscle
• Smooth muscle

3. Cardiovascular Physiology (12%)

• Cardiac pump
• Electrophysiology of the heart
• Hemodynamics
• Regulation of circulation
• Circulation in organs
• Lymphatics
• Hematology and immunity

4. Respiratory Physiology (11%)

• Mechanics of breathing
• Ventilation, lung volumes and capacities
• Regulation of respiration
• O₂ and CO₂ transport
• Gas exchange

5. Body Fluids and Renal Physiology (11%)

• Regulation of body fluids/micturition
• Glomerular filtration
• Tubular exchange
• Acid-base balance

6. Gastrointestinal Physiology (10%)

• Ingestion/motility
• Digestion/secretion
• Absorption
• Regulation of GI function

7. Reproductive Physiology (10%)

8. Endocrine Physiology (12%)

• Secretion of hormones
• Action of hormones
• Regulation

9. Exercise and Sports Physiology (10%)

 1. Carbohydrates (13%)

• Metabolism
  • Catabolic pathways
  • Anabolic pathways
• Chemistry
  • Structure
  • Properties
  • Function
• Nutritional Concepts
  • Food sources
  • Digestion

2. Lipids (12%)

• Metabolism
  • Catabolic pathways
  • Anabolic pathways
• Chemistry
  • Structure
  • Properties
  • Function
  • Transport
• Nutritional Concepts
  • Food sources
  • Digestion

3. Proteins, Amino Acids and Peptides (13%)

• Amino acid metabolism
  • Catabolic pathways
  • Anabolic pathways
• Chemistry
  • Structure
  • Properties
  • Function
• Nutritional concepts
  • Food sources
  • Digestion

4. Enzymes (12%)

• Classification and function
• Kinetics and regulation

5. Hormones (13%)

• Metabolic effects of specific hormones
  • Carbohydrate metabolism
  • Lipid metabolism
  • Protein metabolism
• General properties
  • Chemistry
  • Mechanism of action

6. Nucleotides and Nucleic Acids (12%)

• Metabolism of purines and pyrimidines
• Chemistry
  • Structure
  • Properties
  • Function
• DNA, RNA, and protein synthesis

7. Vitamins and Minerals (13%)

• Chemistry
  • Structure
  • Properties
  • Function
  • Coenzyme precursors
• Nutritional concepts
  • Food sources
  • Absorption of metabolism
  • Storage

8. Biochemical Energetics (12%)

• Basic concepts
  • High-energy phosphate compounds
  • Oxidation-reduction reactions
• Citric acid cycle
• Oxidative phosphorylation and electron transport system

1. Fundamentals of Pathology (15%)

• Disease at the cellular level
• Inflammation and repair
• Neoplasia
• Hemodynamic disorders

2. Genetic and Congenital Disorders (10%)

• Chromosomal disorders
• Inborn errors of metabolism
• Congenital disorders

3. Disorders of the Immune System (14%)

• Hypersensitivity reactions
• Autoimmune diseases
• Immunologic deficiencies

4. Environmental and Nutritional Diseases (13%)

5. Disorders of the Musculoskeletal System (16%)

• Bone
• Joint
• Muscle

6. Disorders of the Nervous System (16%)

• Central nervous system
• Peripheral nervous system

7. Diseases of the Organ Systems (16%)

• Cardiovascular
• Gastrointestinal
• Respiratory
• Genitourinary
• Endocrine
• Blood and lymphatics

1. Immunology (18%)

• Cells of the immune system
• Antigens, antibodies and complement
• Hypersensitivities and immunopathologies
• Immunization/vaccination
• Assessment of immune responses/serology

2. Bacteria (18%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

3. Viruses and Prions (18%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

4. Fungi (15%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

5. Parasites (15%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

6. Epidemiology and Disease Control (16%)

• Health agencies and reporting/monitoring
• Prevention, identification and control methods for communicable diseases
• Population health assessments
• Emerging diseases